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まひ障害リソースセンター

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脳性麻痺の研究 / Cerebral Palsy Research

生物医学の研究により、脳性麻痺の予防や、脳性麻痺患者の診断や治療が進んできました。脳性麻痺症例の約70%は分娩前に発症し、20%は分娩時に発生し、約10%は生後2年間以内に発生します。これら3つの場合における危険因子は既に解明されており、それには、子宮内感染、脳内出血、痙攣、呼吸や循環に関する問題、脳卒中、外傷、および胎児の脳に損傷を与える他の原因が含まれます。風疹(三日ばしか)や黄疸のような症状も脳性麻痺の原因になることが知られています。これらの危険因子は、その予防や治療が可能になっています。

未熟児は、臨月で出生した新生児に比べて、約100倍の確率で脳性麻痺が発生します。研究者は、タバコやアルコールや処方箋を必要とする薬剤(抗鬱剤など)、環境有害物質などの危険因子を減少する方策について研究を重ねています。

サイトカインの果たす役割について、活発に研究されています。サイトカインは、細胞やその他の組織の代謝を制御してその活動(免疫系細胞の活性化など)に影響します。サイトカインは細菌の侵入や酸素濃度の低下(低酸素症)や血液流量の低下(虚血)に対する反応で分泌され、発育途上で脳損傷を引き起こす一連の事象と深い関連があります。新生児の脳障害を防止する上で、サイトカインの早期検出が重要です。

脳画像や歩行分析が向上すれば、理学療法、心理療法、行動療法も向上します。投薬や手術や支持器によって筋肉の協調が改善されることがあり、二次的な医学的問題の治療や奇形の軽減に役に立つことがあります。脳性麻痺の管理に理学療法が広く用いられており、医師や両親が最善策を選択する上で大いに役立つことが証明されてきています。

The Alan T Brown Foundation to Cure ParalysisFormed to support research in spinal cord injury.

American Academy for Cerebral Palsy and Developmental Medicine (AACPDM)A multidisciplinary scientific society devoted to the study of cerebral palsy and other childhood onset disabilities, to promoting professional education for the treatment and management of these conditions, and to improving the quality of life for people with these disabilities.

The Australian Spinal Research FoundationFunds research for treatments of spinal cord injuries.

The Amyotrophic Lateral Sclerosis Association (ALS)Funds numerous projects to develop treatments for ALS (Lou Gehrig’s disease).

Center WatchClinical trials listing of industry professionals, patients and info.

Dana FoundationA nonprofit organization that provides reliable, accessible information on brain and spinal cord research.

The Department of Veterans Affairs (VA)Funds research to develop therapies for many conditions related to paralysis, including traumatic injury and chronic disease.

The International Spinal Research TrustISRT is the only charity based in the United Kingdom dedicated to funding research to end the permanence of paralysis caused by spinal cord injury.

International Campaign for Cures of Spinal Cord Injury ParalysisA group of organizations around the world that together fund about $25 million a year in SCI research. The members include: the Miami Project to Cure Paralysis, Christopher Reeve Paralysis Foundation, Australasian and International Spinal Research Trusts, Paralyzed Veterans of America, Rick Hansen Institute and Kent Waldrep National Paralysis Foundation.

March of Dimes Birth Defects FoundationOffers information about the four major problems that threaten the health of America's babies: birth defects, infant mortality, low birthweight, and lack of prenatal care. Good resources and information on Spina Bifida.

The Mike Utley FoundationProvides financial support of selected research, rehabilitation and education programs on spinal cord injuries.

Myelin ProjectFunds research for diseases related to loss of myelin (a fatty insulation on nerve fibers) including multiple Sclerosis and leukodystrophy.

The National Multiple Sclerosis Society (NMSS)Funds millions of dollars in research each year seeking therapies for MS. Site includes an overview of MS neuroscience, deep detail and progress reports.

National Institute of Neurological Disorders and StrokeProvides research overviews for all diseases and conditions related to paralysis.

The Paralysis Project of AmericaBased in Los Angeles, The Paralysis Project of America funds selected scientific and clinical studies that focus on spinal cord repair and regeneration.

The Rick Hansen Man in Motion FoundationCreated in Canada in 1988 to support spinal cord injury research, as well as wheelchair sport, injury prevention and rehabilitation programs.

SpinalCure AustraliaEstablished in 1994 to fund scientific research to find a cure for paralysis.

United Cerebral Palsy (UCP)UCP's mission is to advance the independence, productivity, and full citizenship of people with cerebral palsy and other disabilities, through a commitment to the principles of independence, inclusion, and self-determination.

United Cerebral Palsy Research and Educational Foundation (UCPREF)The mission of UCPREF is to provide “hope through research” to the entire community of people who care about cerebral palsy and developmental disabilities. UCPREF provides financial support to research relevant to cerebral palsy and other developmental disabilities.

UCPWebsite on accessible public transportation.

Library Books and VideosFind resources within the PRC library catalog.

Quality of Life Grants DatabaseFind resources within the PRC Quality of Life Grants Database. Search by Zip Code, State or an Entire Category.

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自由: まひ状態によって影響される人々とそれらを気遣う人のための広範囲情報用具。 英語およびスペイン語。 あなたのコピーを要求しなさい. オンライン版を読みなさい.

 

The information provided in the Paralysis Resource Center was supported by Grant/Cooperative Agreement Number 1U59DD000338 from the Centers for Disease Control and Prevention (CDC). The contents are solely the responsibility of the authors and do not necessarily represent the official views of CDC.